Skin and soft tissue infection (i.e. cellulitis).
Surgical prophylaxis.
Susceptible Staphylococcal, Streptococcal and Gram negative infections.
Allergy (immediate or delayed).
Can cause positive Coombs, cytopenias.
Probenecid - prolonged half-life. Drug interaction has been used therapeutically to give once daily cefazolin
Antimicrobial class: 1st Generation Cephalosporin
Average serum half life:
Route of Elimination: excreted unchanged in urine