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Gastrointestinal & Intra-Abdominal Infections
Peptic Ulcer Disease

Peptic Ulcer Disease

Likely Causative Organism

Helicobacter pylori

Empiric Antibiotics: Triple Therapy

PPI PO q12h

PLUS

PLUS

OR

Alternative Antibiotics: Bismuth Quadruple Regimen

PPI PO q12h

PLUS

Bismuth subsalicylate 300mg

OR

Bismuth subcitrate 120-300mg PO q6h

PLUS

Tetracycline hydrochloride 500mg PO q6h

PLUS

Duration

14 days

Note

  • Omeprazole 20 mg PO q12h
  • Pantoprazole 40 mg PO q12h
  • Lansoprazole 30 mg PO q12h
  • Esomeprazole 20 mg PO q12h
  • Rabeprazole 20 mg PO q12h