Gastrointestinal & Intra-Abdominal Infections
Biliary Tract Infections

Biliary Tract Infections

Likely Causative Organisms

Enterobacteriaceae

Klebsiella sp.

Alternative Antibiotics

OR

Cefoperazoe-Sulbactam 3gm IV 12 hourly

+/-

Duration of Therapy

7-10 days

Recommendations

Surgical or endoscopic drainage to be considered if there is biliary obstruction, as antibiotics will not enter bile in the presence of obstruction

If high local prevalence of ESBL producing E. coli, Klebsiella sp. strains, start with Meropenem as first line antibiotic, and then de-escalated once antibiotic susceptibility is known