Antimicrobials
Clindamycin

Clindamycin

High
Excellent

Dosing

General Information

  • Anaerobic infections above the diaphragm, especially dental infection
  • Gram positive skin and soft tissue infections including necrotizing fasciitis as an adjunctive agent to a beta lactam for reducing toxin production
  • Skin & soft tissue infections involving susceptible MRSA
  • Susceptible infections and surgical prophylaxis in setting of IgE mediated beta-lactam allergy
  • For decreasing toxin production in toxic shock syndrome

Monitor for diarrhea.

  • High risk of Clostridium difficile infection
  • Cytopenia
  • Abnormal liver enzymes
  • Muscle relaxants, e.g. atracurium, baclofen, diazepam
  • St. Johns Wort

Antimicrobial class: Lincosamide

Pregnancy category: B