General Spectrum of Activity
Same toxicities as conventional Amphotericin B but with less frequency.
Careful attention to electrolyte and fluid status with boluses (usually 500 mL) of NS before and after infusion, as well as K and Mg supplementation as needed.
Antimicrobial class: Antifungal - polyene - Lipid formulations (designed to minimize toxicity)
Pregnancy category: B
Biliary penetration: Therapeutic
Lung penetration: Therapeutic
Urine penetration: Poor - use traditional Amphotericin