Neisseria meningitidis

Neisseria meningitidis


Droplet / Contact Precautions


General Information

  • Fastidious encapsulated gram negative diplococci
  • 13 different serogroups

Normal flora. Humans are the reservoir.

Quadrivalent vaccine prevents disease by serogroups A/C/W-135/Y.

Occurs in outbreaks particularly in crowded settings.

Colonizer and cause of invasive disease:

  • Meningitis (2nd most common cause)
  • Meningococcemia


  • Petechial rash
  • Pneumonia


  • Septic arthritis
  • Pericarditis
  • Conjunctivitis
  • Others

Generally of little significance when cultured from nonsterile sites e.g. genital, pharynx.

Contact and droplet precautions until 24hrs of appropriate antimicrobial therapy.

Prophylaxis may be required for close contacts and healthcare workers (Rifampin PO x2 days, Ciprofloxacin PO 1x, Ceftriaxone IM 1x).

Vaccine Quadrivalent meningococcal vaccine (covers serotypes A, C, Y, W-135) for those at risk.