General Spectrum of Activity
Suspected or proven MRSA, coagulase-negative Staphylococcal infections, Enterococcal infections.
Collect trough 0-1h before 3rd dose if abnormal/fluctuating renal function
Piperacillin-Tazobactam (Tazocin) and Vancomycin concomitant administration may lead to synergistic nephrotoxicity.
Aminoglycosides may potentiate nephrotoxicity.
May enhance neuromuscular blockade of NM blocking agents.
Careful with concomitant nephrotoxins.
Do not administer faster than 1g/hr due to increased risk of Red man's syndrome
Antimicrobial class: Glycopeptide
Pregnancy category: C
Average serum half life: 8 hours
Urine penetration: Therapeutic
Lung penetration: Therapeutic
CSF penetration: Moderate
Biliary penetration: Moderate