Antimicrobials
Meropenem

Meropenem

Medium
N/A

Dosing

General Information

Therapy of serious, often nosocomial infections involving resistant gram negative organisms

  • Immediate and delayed-type allergy
  • GI disturbance
  • Cytopenias, positive Coombs
  • Liver enzyme abnormalities
  • Valproic acid - Carbapenems decrease valproate levels and may decrease seizure threshold
  • Probenecid - May increase meropenem levels (avoid use if possible)

Antimicrobial class: Carbapenem

Pregnancy category: B

Average serum half life: 1 hour

Biliary penetration: Therapeutic

CSF penetration: Moderate

Lung penetration: Therapeutic

Urine penetration: Therapeutic