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Antimicrobials
Ceftriaxone

Ceftriaxone

High
N/A

Dosing

General Information

Empiric therapy of:

  • Community acquired pneumonia
  • Bacterial meningitis
  • Pyelonephritis
  • Nosocomial gram negative infections (except Pseudomonas)
  • Spontaneous bacterial peritonitis
  • Hospitalized community or nursing home acquired pneumonia in combination with a macrolide
  • Allergy/rash (immediate or delayed)
  • Cytopenias
  • Eosinophilia
  • Hepatic & renal laboratory abnormalities
  • Pseudocholelithiasis
    • Unclear clinical significance
    • Uncommonly symptomatic, but frequently by ultrasound gallbladder sludge

Do not co-administer with calcium-containing solutions (including Ringer's lactate)

Contraindicated in neonates (Age 0-28 days)

Antimicrobial class: Parenteral Cephalosporin - 3rd Generation

Pregnancy category: B

Average serum half life: 8 hours

Urine penetration: Therapeutic

Lung penetration: Therapeutic

CSF penetration: Therapeutic

Biliary penetration: Therapeutic