Cefazolin
Renal

Renal

In the setting of rapidly improving/worsening renal function, calculations of eGFR are inaccurate, and dosing should be based on estimated renal function instead.

If worsening renal function, actual GFR is likely lower than calculated.

If improving renal function, actual GFR is likely higher than calculated eGFR.

Not On Dialysis

CrCl <10

50% of usual dose every 24 hours

CrCl 11 - 34

50% of usual dose every 12 hours

CrCl 35 - 55

1-2g IV q8h

CrCl > 55

2g IV q8h