Antimicrobials
Cefazolin

Cefazolin

Medium
N/A

Dosing

General Information

Skin and soft tissue infection (e.g. cellulitis).

Bacteremia and endocarditis.

Surgical prophylaxis.

Susceptible Staphylococcal, Streptococcal and gram negative infections.

Allergy (immediate or delayed).

Can cause positive Coombs, cytopenias, and hepatic and renal laboratory abnormalities.

Probenecid - prolonged half-life. Drug interaction has been used therapeutically to give once daily cefazolin.

Not recommended unless no other alternatives.

Antimicrobial class: 1st Generation Cephalosporin

Pregnancy category: B

Average serum half life: 2 hours

Urine penetration: Therapeutic

Lung penetration: Therapeutic

CSF penetration: Poor

Biliary penetration: Therapeutic