General Spectrum of Activity
Monitor QTc in patients with increased risk
Prolongation of QTc interval. Association with increased cardiovascular mortality in observational studies.
Prolonged half life may contribute to macrolide resistance.
Bioavailability: 37% - low
Antimicrobial class: Macrolide
Pregnancy category: B
Average serum half life: 68 hours
Urine penetration: Poor
Lung penetration: Therapeutic
CSF penetration: Poor
Biliary penetration: Therapeutic