Treatment | Comments |
---|---|
High-Dose Steroids^ | Methylprednisolone 1-2 mg/kg/day divided q8-12h, OR, Dexamethasone 20 mg daily x 5 days, followed by 6-10 mg daily |
Immune Modulator | Baricitinib OR Tocilizumab (if pt meets inclusion criteria**) |
^ insufficient evidence to recommend one steroid over the other
**HFNC, acute BiPAP/CPAP, or mechanical ventilation; CRP ≥ 7.5 mg/dL (w/in past 24 hr); on corticosteroids
Enoxaparin (1st line)
OR
Heparin subcutaneous (2nd line)