Treatment | Comments |
---|---|
Steroids | Dexamethasone 6 mg IV/PO daily up to 10 days |
Remdesivir* | 200 mg IV x 1 dose, followed by 100 mg IV daily x 4 days |
Baricitinib | Consider if steroids contraindicated |
*It is unclear whether Remdesivir is beneficial >7 days beyond symptom onset in immunocompetent patients.
*Therapy should be stopped after 3 days if patient no longer requires oxygen
Treatment | Comments |
---|---|
High-dose steroids* | Methylprednisolone 1-2 mg/kg/day divided q8-12, OR, Dexamethasone 20 mg daily x 5 days, followed by 6-10 mg daily for 10 days |
*Insufficient evidence to recommend one steroid over the other
Treatment | Comments |
---|---|
Baricitinib | 4 mg daily up to 14 days |
Tocilizumab* | x 1 (If pt meets inclusion criteria**) |
*EUA status, requires documentation of EUA criteria in a progress note
**HFNC, acute BiPAP/CPAP, or mechanical ventilation; CRP ≥ 7.5 mg/dL (w/in past 24 hr); on corticosteroids
Enoxaparin (1st line)
OR
Heparin subcutaneous (2nd line)