Age > 55
Pre-existing pulmonary disease
Chronic kidney disease
Diabetes with A1c > 7.6%
History of hypertension
History of cardiovascular disease
Use of biologics for immune suppression
History of transplant or other immunosuppression
All patients with HIV (regardless of CD4 count)
Healthcare personnel with significant aerosolizing exposure
Respiratory rate > 24
Heart rate > 125 bpm
SpO2 < 90% on room air
D-dimer > 1 mcg/mL (1000 ng/mL)
CPK > 2 x ULN
CRP > 10 mg/dL (100 mg/L)
LDH > 245 units/L
Elevated troponin
Admission absolute lymphocyte count < 0.8
Ferritin > 500 ug/L
There are no active inpatient clinical trials at this time
Note: Dexamethasone does not need to be tapered in most patients for Covid-19 due to its long biological half-life (36 – 72hr)