Intrinsic resistance to ampicillin and lower generation cephalosporins.
Usually susceptible to fluoroquinolones, TMP-SMX, and aminoglycosides which are appropriate targeted therapy options.
Susceptible to carbapenems.
With exposure to beta-lactams, induction or de-repression can occur and confer resistance to third generation cephalosporins.
Using Pip-Tazo and Ceftriaxone when reported as susceptible is likely reasonable for simple infections requiring short duration.
Cefepime when reported as susceptible is reasonable for most infections.
Life-threatening and Bloodstream infections should be managed with a carbapenem.