Pathogens
Enterobacter aerogenes

Enterobacter aerogenes

Precautions

See 'Additional Information'

General Information

Most Infections

  • Carbapenem: preferred empirically in severe infections until susceptibility known.
  • Cefepime is acceptable only when the MIC is ≤ 2
    • Cefepime MICs ≥4 may have ESBL co-production rendering cefepime less effective.
  • Definitive Therapy (if susceptible)
    • Fluoroquinolones
    • Cefepime (MIC ≤ 2)
    • Bactrim

Only acceptable in mild infections/cystitis (if susceptible)

  • Zosyn
  • Ceftriaxone

Cystitis

  • Nitrofurantoin (cystitis only)
  • Ceftriaxone
    • Note: oral 3rd gen cephs should not be used unless other options (e.g. nitrofurantoin, Bactrim, fluoroquinolone) are inappropriate
  • Fosfomycin should not be routinely used, has unpredictable coverage against Enterobacter sp. due to presence of FosA gene that can hydrolyze Fos and may lead to clinical failure

Fermenting gram negative rod, of the Enterobacteriaceae family

GI flora, especially in hospitalized patients.

Infection usually in nosocomial setting.

Nosocomial infections:

  •  Pneumonia (HAP)
  • UTI
  •  Wound infections
  • Prosthetic device and line infections

May require contact precautions if highly resistant.