Clarithromycin
Renal

Renal

In the setting of rapidly improving or worsening renal function, calculations of CrCl are inaccurate. Dosing should be based on estimated renal function instead.

If improving renal function, actual CrCl is likely higher than calculated CrCl.

If worsening renal function, actual CrCl is likely lower than calculated CrCl.

Not On Dialysis

CrCl 0 - 10

500mg PO q24h

CrCl 10 - 50

500mg PO q12h

CrCl > 50

500mg PO q12h

Intermittent Dialysis

500mg PO q24h

Dose after dialysis on HD days