Antimicrobials
Fosfomycin

Fosfomycin

Restricted
C difficile risk
Low
Oral Bioavailability
Moderate

Dosing

Female, Uncomplicated UTI 3g PO once

Complicated or male UTI 3g PO q2-3days x 3 doses

Intermittent Dialysis Dose post-hemodialysis

General Information

Urinary Tract Infection, especially involving ESBL producing organisms

Offlabel - Prostatitis

  •  GI upset, especially diarrhea

  •  Headache

  •  Eosinophilia, neutropenia

  •  Hypokalemia

No significant interactions

Antimicrobial class: Phosphonic acid derivative

Pregnancy category: B

Average serum half life: 6 hours

Urine penetration: Therapeutic