Oseltamivir
Renal

Renal

In the setting of rapidly improving or worsening renal function, calculations of CrCl are inaccurate. Dosing should be based on estimated renal function instead.

If improving renal function, actual CrCl is likely higher than calculated CrCl.

If worsening renal function, actual CrCl is likely lower than calculated CrCl.

Not On Dialysis

CrCl 0 - 10

30 mg PO q48h

CrCl 10 - 30

30 mg PO q24h

CrCl 30 - 60

30 mg PO q12h

Intermittent Dialysis

30 mg PO load, then 30 mg PO after each HD session for 5 day period

Continuous Dialysis

75 mg PO q24h