Uncomplicated cystitis in females ONLY. Do not use for urinary infections with systemic symptoms, or when CrCL is LESS THAN 30 ml/min. Do NOT use for most males with UTI; may have some role in male CAUTI.
Interstitial pneumonitis and fibrosis especially with prolonged use.
Peripheral neuropathy.
Antacids decrease absorption
Think of this drug as a urinary antiseptic. Dosing varies based on formulation choice. Careful with product selection.
Antimicrobial class: Nitrofuran
Pregnancy category: B
Average serum half life: 1 hour
Biliary penetration: None
CSF penetration: None
Lung penetration: None
Urine penetration: Therapeutic