Antimicrobials
Nitrofurantoin

Nitrofurantoin

Low
Excellent

Dosing

General Information

Uncomplicated cystitis in females ONLY. Do not use for urinary infections with systemic symptoms, or when CrCL is LESS THAN 30 ml/min. Do NOT use for most males with UTI; may have some role in male CAUTI.

Interstitial pneumonitis and fibrosis especially with prolonged use.

Peripheral neuropathy.

Antacids decrease absorption

Think of this drug as a urinary antiseptic. Dosing varies based on formulation choice. Careful with product selection.

Antimicrobial class: Nitrofuran

Pregnancy category: B

Average serum half life: 1 hour

Biliary penetration: None

CSF penetration: None

Lung penetration: None

Urine penetration: Therapeutic