Macrobid 100mg PO BID
eGFR 0 - 30eGFR > 30Not recommendedUsual dose
Uncomplicated cystitis in females ONLY. Do not use for urinary infections with systemic symptoms, or when CrCL is LESS THAN 30 ml/min.
Do NOT use for most males with UTI; may have some role in male CAUTI.
Interstitial pneumonitis and fibrosis especially with prolonged use.
Antacids decrease absorption
Think of this drug as a urinary antiseptic.
Dosing varies based on formulation choice. Careful with product selection.
Antimicrobial class: Nitrofuran
Pregnancy category: B
Average serum half life: 1 hour
Biliary penetration: None
CSF penetration: None
Lung penetration: None
Urine penetration: Therapeutic