Pseudomonal and other gram negative infections.
Inhaled form used in cystic fibrosis.
Monitor creatinine at least 3 times/week. Discontinue if any signs of ototoxicity.
Can exacerbate neuromuscular blockade
Neuromuscular blockade agents - Respiratory paralysis.
Formal audiology assessment if planning to use aminoglycoside for >7d or if symptoms develop.
Inform patient of risk of ototoxicity and to report any symptoms
Antimicrobial class: Aminoglycoside
Pregnancy category: D
Average serum half life: 3 hours
Urine penetration: Therapeutic
Lung penetration: Therapeutic
CSF penetration: Poor
Biliary penetration: Moderate