Cephalexin

C difficile risk
Medium
Oral Bioavailability
Moderate

Dosing

500-1000mg PO q6-8h

CrCl 0 - 10CrCl 10 - 29CrCl > 50250 - 500 mg PO q12-24h250 - 500 mg PO q8-12h500 - 1000 mg PO q8-6h

250 - 500 mg PO q24h

Dose after dialysis on hemodialysis days

General Information

  •  Uncomplicated skin and soft tissue infection

  •  MSSA infections

  •  Allergy/rash (immediate or delayed)

  •  Positive Coombs

  •  Cytopenias

  •  Eosinophilia

  •  Hepatic & renal laboratory abnormalities

Increases metformin levels

Antimicrobial class: First Generation Cephalosporin.

Pregnancy category: B

Biliary penetration: Moderate

CSF penetration: Poor

Lung penetration: Moderate

Urine penetration: Therapeutic

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