Broad gram negative coverage including Pseudomonas, generally used for nosocomial infections including post-neurosurgical meningitis, or other infections based on susceptibilities.
Notable lack of gram positive activity versus other cephalosporins.
Often used for nosocomial infections where psuedomonas aeruginosa is a consideration
Allergy (immediate and delayed).
Note potential cross-reactivity with aztreonam based on side chain.
Concurrent use of CEFTAZIDIME and WARFARIN may result in an increased risk of bleeding
Antimicrobial class: 3rd generation Cephalosporin
Pregnancy category: B
Average serum half life: 1-2 hours (prolonged in renal impairment)
Biliary penetration: Moderate
CSF penetration: Therapeutic
Lung penetration: Therapeutic
Urine penetration: Therapeutic
Route of Elimination: Urine (80% to 90% as unchanged drug)