Spectrum Of Activity
Usual indications 600 mg IV q8h OR 300-450mg PO Q6-8h
Necrotizing SSTI or toxic shock syndrome 900mg IV q8h
Certain anaerobic infections, especially dental infection. Not for intraabdominal infections.
Gram positive skin and soft tissue infections including necrotizing fasciitis as an adjunctive agent to a beta lactam for reducing toxin production by certain organisms.
Skin & soft tissue infections involving susceptible MRSA.
Susceptible infections and surgical prophylaxis in setting of IgE mediated beta-lactam allergy.
Monitor for diarrhea.
C. difficile infection
Muscle relaxants, e.g., atracurium, baclofen, diazepam.
St. Johns Wort
Antimicrobial class: Lincosamide
Pregnancy category: B
Average serum half life: 2.4 hours
Biliary penetration: Therapeutic
CSF penetration: Poor
Lung penetration: Therapeutic
Urine penetration: Poor