Ertapenem

Restricted
C difficile risk
Medium
Oral Bioavailability
N/A

Dosing

1g IV q24h

CrCl 0- 30CrCl > 30500mg IV q24h1g IV q24h

500mg IV daily

Dose after dialysis on HD days

General Information

Targeted therapy of ESBL infections and other resistant gram negative infections.

  • Immediate and delayed-type allergy

  • GI disturbance

  • Cytopenias, eosinophilia, positive Coombs

  • Liver enzyme abnormalities

  • Seizure risk lower than other carbapenems

Antimicrobial class: Carbapenem

Pregnancy category: B

Average serum half life: 4 hours

Biliary penetration: Moderate

Lung penetration: Therapeutic

Urine penetration: Therapeutic

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