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Antimicrobials
Cefadroxil

Cefadroxil

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Medium
Good (70 to 90%)
Non-formulary for inpatients

Spectrum of Activity

General Spectrum of Activity
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Dosing

General Information

Urinary tract infection, skin and soft tissue, streptococcal pharyngitis

  • GI upset, nausea, vomiting, diarrhea
  • Allergy/rash (immediate or delayed)
  • Thrombocytopenia (rare)
  • Increased transaminases (rare)
  • Cefazolin susceptibility may not accurately predict cefadroxil susceptibility for Enterobacterales (~ 90% accuracy). Use caution if prescribing for a Gram-negative infection other than cystitis.
  • For certain Gram-positive infections, cefadroxil q12h may be considered for outpatients who have compliance concerns with cephalexin q6h.

Antimicrobial class: First Generation Cephalosporin.

Pregnancy category: B

Biliary penetration: Poor

CSF penetration: Poor

Lung penetration: Therapeutic

Urine penetration: Therapeutic