Capsules may be opened and mixed with food. Follow instructions in attachment from CDC. Available here.
Capsules should be taken with a full glass of water within 30 minutes after eating a full meal of moderate or high fat (ideally about 600 calories and 25 grams of fat) in order to improve bioavailability.
CDC holds an EA-IND to allow access to and use of TPOXX for treatment of non-variola orthopoxvirus infections in adults and children.
Antimicrobial class: Antiviral
Pregnancy category: Undetermined
Average serum half life: 21 hr (IV), 19 hr (PO)
Urine penetration: Therapeutic