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Antimicrobials
Cefpodoxime

Cefpodoxime

C difficile risk
High
Oral Bioavailability
Moderate
Cost
Non-formulary for inpatients

Spectrum Of Activity

General Spectrum of Activity

Dosing

Adult

  • SSTI: 400 mg PO BID

  • All other indications: 200 mg PO BID

Renal

CrCl 0 - 29CrCl > 30- SSTI: 400 mg PO q24h

  • All other indications: 200 mg PO q24hUsual dosing

200 - 400 mg PO TIW after HD

General Information

Pharmacology

Antimicrobial class: Oral cephalosporin - 3rd generation

Pregnancy category: B

Average serum half life: 2 hours

Biliary penetration: Therapeutic

CSF penetration: Poor

Lung penetration: Therapeutic

Urine penetration: Therapeutic

Route of Elimination: Renal, bile