C difficile risk
Oral Bioavailability


CrCl 0 - 29300 mg PO q24h

300 mg PO q48h + an extra dose after HD

General Information

  • Pneumonia

  • Intra-abdominal infections

  • SSTI's

  • UTI's

  • Nausea, diarrhea

  • Allergy/rash (immediate or delayed)

  • Cytopenias (<1%)

  • Hepatic (hepatitis, transaminitis) <1%

Antimicrobial class: Oral Cephalosporin - 3rd Generation

Pregnancy category: B

Average serum half life: 2 hours

Biliary penetration: Poor

CSF penetration: Poor

Lung penetration: Therapeutic

Urine penetration: Therapeutic

Route of Elimination: Primarily urine

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