Complicated IAI
Specific Pathogens

Specific Pathogens

Enterococcus species

Cover only if recovered from the blood or infected site.

OR, If susceptible & no allergy

Candida species

Cover only if seen on a Gram stain or growth from a sterile site.

800 mg PO/IV (12 mg/kg) on day 1, then 400 mg q24h PO/IV (6 mg/kg)

OR, IF CRITICALLY ILL

Resistant Gram Negative Species

  • Includes: ESBLs, MDR Pseudomonas, AmpC organisms
  • Cover only if isolation of resistant strains from sterile site.
  • Antibiotic choice depends on organism; consider ID consult