Involves source organ only
Contamination or inflammation that does not extend beyond the source
Disease is completely excised at the time of operation
Examples: early traumatic perforation, simple appenditicitis, non-perforated diverticulitis
Extends beyond source organ
Contamination or inflammation extends beyond the organ that is the source of the infection
Localized peritonitis (i.e., abdominal abscess)
Diffuse peritonitis
Characterized by pus or an exudate at the time of source control
Guideline originally sourced from Markham Stouffville Hospital and adapted by Joseph Brant Hospital
Mazuski JE, Tessier JM, May AK, et al. The Surgical Infection Society Revised Guidelines on the Management of Intra-Abdominal Infection. Surg Infect (Larchmt). 2017;18(1):1-76.
de Jonge SW, Boldingh QJJ, Solomkin JS, et al. Effect of postoperative continuation of antibiotic prophylaxis on the incidence of surgical site infection: a systematic review and meta-analysis [published online ahead of print, 2020 May 26]. Lancet Infect Dis. 2020;S1473-3099(20)30084-0
Doyle J, Nathens A, Morris A, et al. Best Practice in General Surgery Guideline #4: Management of Intra‐Abdominal Infections. TASC Nov 2011. 1-26
Sartelli, M., Chichom-Mefire, A., Labricciosa, F.M. et al. The management of intra-abdominal infections from a global perspective: 2017 WSES guidelines for management of intra-abdominal infections. World J Emerg Surg 12, 29 (2017).
The Johns Hopkins University (2020) John Hopkins ABX Guide (1.27) [Mobile App] Retrieved from: www.hopkinsguides.com
Antimicrobial Therapy Inc (2020) The Sanford Guide (4.2) [Mobile App] Retrieved from: www.sanfordguide.com/
