Complicated IAI

Complicated IAI


  • Involves source organ only

  • Contamination or inflammation that does not extend beyond the source

  • Disease is completely excised at the time of operation

  • Examples: early traumatic perforation, simple appenditicitis, non-perforated diverticulitis

  • Extends beyond source organ

  • Contamination or inflammation extends beyond the organ that is the source of the infection

  • Localized peritonitis (i.e., abdominal abscess)

  • Diffuse peritonitis

  • Characterized by pus or an exudate at the time of source control

Additional Information

Guideline originally sourced from Markham Stouffville Hospital and adapted by Joseph Brant Hospital

  • Mazuski JE, Tessier JM, May AK, et al. The Surgical Infection Society Revised Guidelines on the Management of Intra-Abdominal Infection. Surg Infect (Larchmt). 2017;18(1):1-76.

  • de Jonge SW, Boldingh QJJ, Solomkin JS, et al. Effect of postoperative continuation of antibiotic prophylaxis on the incidence of surgical site infection: a systematic review and meta-analysis [published online ahead of print, 2020 May 26]. Lancet Infect Dis. 2020;S1473-3099(20)30084-0

  • Doyle J, Nathens A, Morris A, et al. Best Practice in General Surgery Guideline #4: Management of Intra‐Abdominal Infections. TASC Nov 2011. 1-26

  • Sartelli, M., Chichom-Mefire, A., Labricciosa, F.M. et al. The management of intra-abdominal infections from a global perspective: 2017 WSES guidelines for management of intra-abdominal infections. World J Emerg Surg 12, 29 (2017).

  • The Johns Hopkins University (2020) John Hopkins ABX Guide (1.27) [Mobile App] Retrieved from:

  • Antimicrobial Therapy Inc (2020) The Sanford Guide (4.2) [Mobile App] Retrieved from:

Approved: June 2020