SPICEM Organisms (AmpC)

SPICEM Organisms (AmpC)


See 'Additional Information'


General Information

Gram-negative bacteria that have inducible, chromosomal beta-lactamase genes known as AmpC.

Resistance may not be detectable initially, but appears after a period of exposure to beta-lactam antibiotics (induced).

Most AmpC organisms are nosocomially encountered, are GI flora and are part of the Enterobacteriaceae family.

Syndromes caused by the organism that possesses AmpC (see individual organisms).

SPICEM stands for Serratia, Providencia, (Indole positive) Proteus vulgaris, Proteus penneri, Citrobacter, Enterobacter, Morganella and Hafnia

No specific recommendations from IPAC at time of monograph update.