Antimicrobials
Ampicillin

Ampicillin

Low
N/A
$11.64/day (IV)

Dosing

General Information

Pathogen directed therapy for CNS, intravascular, intraabdominal, urinary and other infections especially Enterococcus and Listeria

  • Allergy and rash as for all beta-lactams.
  • EBV related rash (not allergy).
  • Rare: cytopenias, +ve Coombs.

Increased risk of rash with allopurinol.

IV Administration

  • Dilute in 50-100 mL NS and administer over 30 min
  • Max concentration 30 mg/mL

Prescribing Restrictions (IV)

  • None
  • Amoxicillin PO generally preferred over Ampicillin PO due to better bioavailability and less frequent dosing

OPEN BENEFIT (PO): No prescribing restrictions

Antimicrobial class: Aminopenicillin

Pregnancy category: B

Average serum half life: 1 hour

Biliary penetration: Therapeutic

CSF penetration: Therapeutic

Lung penetration: Therapeutic

Urine penetration: Therapeutic