Nephrotoxicity (non-oliguric)
Vestibulocochlear toxicity
Can exacerbate neuromuscular blockade
Allergic reaction
Formal audiology assessment if planning to use aminoglycoside for >7d or if symptoms develop.
Inform patient of risk of ototoxicity and to report any symptoms.
Distribution: distributes adequately into extracellular fluid, ascitic/peritoneal fluid, pericardial fluid, pleural fluid, synovial fluid, and lymphatic fluid. High urinary concentrations. Not well distributed into bile, aqueous humor, bronchial secretions, abscess, sputum, or CSF.