Antimicrobials
Rifapentine

Rifapentine

N/A
Good (70 to 90%)

Spectrum of Activity

Dosing

General Information

Baseline LFTs and every 2-4 weeks during therapy

  • Anemia
  • Lymphocytopenia
  • Diaphoresis
  • Maculopapular rash
  • Pruritis
  • Abdominal pain
  • Anorexia
  • Nausea
  • Vomiting
  • Increased LFTs

Many drug interactions; utilize Clinical Pharmacology or Lexicomp for full list

Inhibits DNA-dependent RNA polymerase in susceptible strains of Mycobacterium tuberculosis (MTB).