Isoniazid
Adult

Adult

Active Tuberculosis

Preferred

Oral: 5 mg/kg once daily

Alternative

15 mg/kg (max 900 mg) 2-3x/week

Latent tuberculosis

Adults (non-pregnant) & children >2 years, including HIV-positive

Oral: 15 mg/kg (max 900 mg/dose) once weekly in combination with rifapentine x 3 months

Adults and children of all ages, including HIV-positive

Oral: 5 mg/kg (max 300 mg) once daily in combination with rifampin x 3 months

Adults and children of all ages, both HIV-negative and HIV-positive

Oral: 5 mg/kg (max 300 mg) once daily for 6 or 9 months