Piperacillin-Tazobactam
Obesity

Obesity

BMI of 30kg/m² or more

Can give 4.5 gm IV loading dose over 30 minutes

Life-threatening infection/resistant pathogens/BMI 50 or more:

  • 4.5 gm IV Q6H (infused over 3 hours)

Critically ill with augmented renal function (>100mL/min):

  • 4.5 gm IV Q8H over 4 hours or
  • 4.5 gm IV Q6H infused over 3 hours