General Spectrum of Activity
Targeted therapy of ESBL infections and other resistant gram negative infections.
Empiric therapy when broad spectrum of carbapenems is desired without the need for anti-pseudomonal activity.
Tier 4 Protected Antimicrobial
Last line option, uncommonly used based upon susceptibility data, may rarely be used for special scenarios
For use in the Short Stay Infusion Clinic only. Restricted from use in all hospitalized patients and in the Emergency Department, excluding a single dose prior to discharge
If patient on outpatient and admitted, pharmacy will therapeutic substitution to meropenem at dosing and frequency appropriate for indication and renal function.
Antimicrobial class: Carbapenem
Pregnancy category: B
Average serum half life: 4 hours
Urine penetration: Therapeutic, excreted 80% into urine
Lung penetration: Therapeutic
Biliary penetration: Moderate
Unlike other carbapenems, Ertapenem does NOT cover Pseudomonas