Cefotaxime
General Spectrum of Activity

General Spectrum of Activity

Gram positive

  • Arcanobacter sp.
  • coag-negative Staphylococcus
  • MSSA
  • Staph. epidermidis, lugdunesis, saprophyticus & anginosus group
  • Groups A, B, C, F, G Streptococci
  • Strep. pneumoniae
  • viridans Streptococci

Gram negative

  • Aeromonas sp.
  • B. burgdorferi
  • Capnocytophaga
  • Eikenella sp.
  • E. coli non-ESBL
  • H. influenzae
  • Kingella sp.
  • Klebsiella oxytoca & pneumoniae
  • Leptospira sp.
  • M. catarrhalis
  • Morganella sp.
  • Neisseria meningitidis
  • Pasteurella species
  • Proteus mirabilis & vulgaris
  • Providencia sp.
  • Salmonella sp.
  • Serratia sp.
  • Shigella sp.
  • V. parahaemolyticus
  • V. vulnificus
  • Y. enterocolitica

Anaerobes

  • Actinomyces sp.
  • Clostridium (not C. difficile)
  • F. necrophorum
  • P. acnes
  • Prevotella melaninogenica
  • Peptostreptococci

Does not cover

  • Enterococci
  • B. fragilis
  • Pseudomonas and other more resistant gram negatives
  • ESBL or AmpC producing Enterobacteriaceae
  • Listeria
  • Not the agent of choice for Staphylococcal infections