Prophylaxis/treatment of bite wounds.

Polymicrobial infections of the respiratory tract or abdomen.

Skin and soft tissue infections.

Tier 1 Protected Antimicrobial

• Narrow spectrum, possible transition for discharge, IV to PO

• Strategy: Total EBM duration set (inpatient and outpatient)

For prolonged therapy, monitor liver enzymes and function.

• Allergy/rash (immediate or delayed)

• Note EBV related rash

• Cytopenias

• Diarrhea

• Hepatotoxicity due to clavulinate - usually mild, liver failure is rare.

Increased risk of rash with allopurinol

Antimicrobial class: Aminopenicillin + Beta-lactamase inhibitor

Pregnancy category: B

Average serum half life: 1 hour

Urine penetration: Therapeutic

Lung penetration: Therapeutic

Biliary penetration: Therapeutic