Utilize the Severe Sepsis/Septic Shock guidelines
Dose recommendations are based on patients with normal renal function. Refer to dosing in renal impairment.
These guidelines may not be appropriate for patients with a history of multi-drug resistant organisms. Consider infectious disease consultation.
Altered mental status alone is NOT an indication for UA and cultures
Severe Sepsis/Septic Shock
Neutropenic Fever
Screening for Urologic Procedures
Screening in pregnancy
Treatment of asymptomatic bacteriuria increases risk of adverse events without improving outcomes, except in specific populations:
Pregnancy
Undergoing endourological procedures
ID consultation should be considered for patients with history of recurrent UTIs or multi-drug resistant organisms
Bacteria (≥ 105 CFU/mL or ≥ 108 CFU/L) in the urine in the absence of symptoms
Community onset or hospitalized < 48 hours
Hospitalized > 48 hours
These recommendations are meant to guide empiric therapeutic decision making and are not meant to replace sound clinical decision making. Definitive therapy should be based on culture and susceptibility reports
Regina Ianni, PharmD
Kyle D. Massey, PharmD
Rebekah Gass, MD
Brian McCullough, PharmD
Guidelines