Antimicrobials
Cefepime

Cefepime

C difficile risk
High
Oral Bioavailability
N/A
Cost
IV: $$

General Information

Preferred Pseudomonas

Broad spectrum antimicrobial with gram positive and gram negative coverage including Pseudomonas.

Used for nosocomial infections

  • Allergy (immediate & delayed)

  •  Positive Coombs

  •  Cytopenias

  •  Non-convulsive status epilepticus

  • Neurotoxicity - Prolonged high-dose exposure in renal impairment; atypical when dose is adjusted for renal function

Antimicrobial class: 4th generation Cephalosporin

Pregnancy category: B

Average serum half life: 2 hours

Biliary penetration: Moderate

CSF penetration: Therapeutic

Lung penetration: Therapeutic

Urine penetration: Therapeutic