Piperacillin-tazobactam 3.375 g IV q6h
OR
Meropenem 500 mg IV q6h
Vancomycin 25 to 30 mg/kg IV x 1 dose, then 15 mg/kg IV q8–12h based on actual body weight
MRSA Risk Factors:
Dose adjustment require in renal impairment for all above antimicrobials.