Lung - Community acquired

Suspected Microbes

Varies by setting

Community Acquired Pneumonia - Initial Treatment

PLUS

Alternatively, consider

  • If Legionella strongly suspected

  • Exercise caution due to association with C. difficile and MRSA

  • Dose adjustment required for renal impairment

OR

  • Exercise caution due to association with C. difficile and MRSA

IF IN ICU ON Moxifloxacin OR levoFLOXacin, CONSIDER ADDING:

  • Dose adjustment required for renal impairment

Aspiration Pneumonia Suspected - Initial Treatment

PLUS

If Risk Factors for MRSA, then consider ADDING to the above regimens:

  • Target trough: 10 to 15 mg/L

  • Consider capping the loading dose at a maximum of 3,000 mg and maintenance doses at a maximum of 2,000 mg.

  • Dose adjustment required in renal dysfunction.

  • History of MRSA infection or colonization

  • Household contact with a MRSA colonized individual

  • IV drug use

  • Homelessness

  • Incarcerated persons

  • Recent travel to or residing in an MRSA endemic region or community

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