High Risk

Microbiology

Based on patient evaluation, consider obtaining cultures before start of antimicrobial therapy and/or repeat if not improving after 72 hours of antimicrobial therapy

Treatment Considerations

If a patient has received an antibiotic in the last 3 months the therapy chosen should be a regimen based on a different mechanism of action regardless of the clinical success

Tailor antibiotic therapy for sputum culture results if available

Dose adjustment required in renal impairment for all antimicrobials outlined below except cefTRIAXone

Oral Therapy

OR

Alternative empiric regimen

OR

Alternative empiric regimen

Intravenous Therapy

Preferred empiric regimen

OR

Alternative empiric regimen

Duration

5-7 days

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