Doxycycline
General Spectrum of Activity

General Spectrum of Activity

Gram positive:

  • Staphylococcus including many MRSA (should NOT be used for MSSA or MRSA bloodstream infections)
  • Streptococcus pneumoniae

Gram negative:

  • M. catarrhalis
  • H. influenzae

Oral anaerobes:

  • Actinomyces
  • Prevotella
  • Clostridia spp. (not C. difficile)
  • Peptostreptococci

Others:

  • Borrelia burgdorferi (Lyme)
  • Syphilis (2nd line)
  • Q-fever
  • Mycoplasma
  • Chlamydophila
  • Rickettsia