Clarithromycin
Renal

Renal

In the setting of rapidly improving or worsening renal function, calculations of CrCl are inaccurate. Dosing should be based on estimated renal function instead.

If improving renal function, actual CrCl is likely higher than calculated CrCl.

If worsening renal function, actual CrCl is likely lower than calculated CrCl.

Not On Dialysis

CrCl 0 - 30 mL/min

Clarithromycin or Clarithromycin XL: 500 mg PO q24h

Intermittent Hemodialysis (IHD: 3 times/week)

Clarithromycin or Clarithromycin XL: 500 mg PO q24h

  • Administer dose after dialysis on dialysis days