Amoxicillin-Clavulanate: Oral

Amoxicillin-Clavulanate: Oral



General Information

Prophylaxis and treatment of human and animal bite wounds.

Polymicrobial infections involving the respiratory tract or abdomen.

For prolonged therapy, monitor liver enzymes and function.

  • Allergy/rash (immediate or delayed)
  • Note Epstein–Barr viral related rash
  • Cytopenias
  • Diarrhea (less likely with twice daily dosing regimen using 875 mg tab)
  • C. difficile infection
  • Hepatotoxicity due to clavulanate - usually mild, liver failure is rare

Increased risk of rash with allopurinol

Antimicrobial class: Aminopenicillin + Beta-lactamase inhibitor

Pregnancy category: B

Average serum half life: 1 hour

Urine penetration: Therapeutic

Lung penetration: Therapeutic

Biliary penetration: Therapeutic