Antimicrobials
Amoxicillin-Clavulanate: Oral

Amoxicillin-Clavulanate: Oral

High
Excellent

Dosing

General Information

Prophylaxis and treatment of human and animal bite wounds.

Polymicrobial infections involving the respiratory tract or abdomen.

For prolonged therapy, monitor liver enzymes and function.

  • Allergy/rash (immediate or delayed)
  • Note Epstein–Barr viral related rash
  • Cytopenias
  • Diarrhea (less likely with twice daily dosing regimen using 875 mg tab)
  • C. difficile infection
  • Hepatotoxicity due to clavulanate - usually mild, liver failure is rare

Increased risk of rash with allopurinol

Antimicrobial class: Aminopenicillin + Beta-lactamase inhibitor

Pregnancy category: B

Average serum half life: 1 hour

Urine penetration: Therapeutic

Lung penetration: Therapeutic

Biliary penetration: Therapeutic